The first paper of Mohamed Smaoui has been published today in Biophysical Journal. His works describes a methods to build and predict the shape of Amyloid fibrils with multiple proto-filaments.
On May 13th, we hosted at McGill a one-day bioinformatics retreat with our colleagues from Toronto. The meeting featured two keynotes from Gary Bader (UofT) and Guillaume Bourque (Genome Quebec), ten selected graduate student talks and a poster session. We concluded the retreat with a soccer game... won by UofT!
It is with a lot of sadness that we heard that Philippe Flajolet passed away on March 22th.
On March 28-31 2011, Solomon Shenker will give a talk entitled " Efficient traversal of β-sheet protein folding pathways using ensemble models ", and Jérôme Waldispühl will give a talk entitled " An unbiased adaptive sampling algorithm for the exploration of RNA mutational landscapes under evolutionary pressure " at the the 15th Annual International Conference on Research in Computational Molecular Biology (RECOMB 2011).
On March 2nd 2011, Jérôme Waldispühl will give a lecture entitled " Ensemble Predictions of β-sheet Protein Structures " at the bioinformatics seminar series at computer science and artificial intelligence laboratory at MIT.
Phylo is a casual game which requests the help of the gamers to solve a biological problem. We have been delighted to see that our work get an echo in both communities. We collected below a couple of links to articles published in gaming magazines and professional media.
Phylo, Our human computing framework for comparative genomics is officially released! We published this morning a press release and invite anyone interested in helping science to solve our puzzles. Phylo is now avalailable in two languages: English and French.
Alexander Kawrykow and Gary Roumanis have been awarded at the 2010 McGill Undergarduate Research Conference for their project “Phylo: A human computing framework for comparative genomics”. Congratulations Alex and Gary!
On October 8-9 2010, Jérôme Waldispühl gave an selected talk titled
“ RNAmutants: A computational framework to explore the mutational landscape of structural RNAs.
Theory and applications” at the “RNA-UNY Structure, Function, Application” symposium
hosted by the Hudson valley RNA club in Rensselaerville, NY.
Silmutaneously, Vladimir Reinharz presented his work in a poster titled “Reconstruction of RNA tertiary structures from predicted secondary structures and RNA 3D motifs”.
On September 1st 2010, we held at McGill a symposium on “Computational Models for RNA structures”. This symposium featured seminars given by experts from France and Canada and enabled us to get familiarized with the most up-to-date theoretical frameworks to predict and analyze RNA structures.
Our group works in the computational structural biology area broadly defined.
We develop theoretical models and algorithms to decipher the relationship between
RNA and protein sequences and structures. Predicting molecular structures is not a
finality but a mean to understand the genetic code and biological systems.
Do you want to know how the genomic sequences can create molecular systems and activate cellular functions? Are you wondering how molecular structures could influence the evolution of genomes? Do you want to design artificial molecular systems? If you do, join us! These are some of the questions we are trying to answer.