Open-Phylo is a freely accessible crowd-computing platform that enables any scientist to use crowds of gamers to assist computer programs in solving one of the most fundamental problems in genomics: the multiple sequence alignment problem.

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RNAmutants is an algorithm to predict the effect of mutations on structures and reciprocally the influence of structures on mutations. A tool for molecular evolution studies and RNA design.

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tFolder is a program that enables you to compute coarse grained representations of the energy landscape of β-sheet proteins and to predict their folding pathways. All you need is to enter your sequence and select the maximal number of strands allowed.

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RNA-MoIP is an integer programming framework that refines predicted secondary structures (i.e. removes incorrect canonical base-pairs) to accommodate the insertion of RNA 3D motifs (i.e. hairpins, internal loops and k-way junctions). The predictions can be used as templates to generate complete 3D structures with the MC-Sym program.

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Using statistical mechanics principles, partiFold computes residue contact probabilities and sample super-secondary structures of proteins from sequence only.

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Fibrilizer is a computational tool to build polymorphic amyloid fibrils at an atomic level resolution and identify stability regions through point-wise mutations that decrease the amyloidogenicity of protein sequences while conserving their native folding properties.

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SPARCS is a program to analyze structured and unstructured regions in coding RNA sequences. SPARCS samples random sequences preserving both the amino acid sequence and the dinucleotide statistics that enable us to calculate accurate z-score values.

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A challenging flash game in which every completed puzzle contributes to improve multiple sequence alignment data.

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IncaRNAtion is a novel approach to design RNA sequences folding into target secondary structures with a predefined nucleotide distribution. It can also be used to generate seeds for classical RNA design software such as RNAinverse and improve their performance.

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CorRna is a program that searches the mutational landscape of a given RNA sequence for mutations that will significantly alter the RNA folding properties.

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RNApyro is a program to correct point-wise errors in sequencing data using RNA secondary structure informations. In particular, it is designed to correct errors for metagenomics data.

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